RTS-1C is a personal bioreactor that utilizes patented Reverse-Spin® technology that applies non-invasive, mechanically driven, low energy consumption, innovative type of agitation where cell suspension is mixed by the singleuse falcon bioreactor tube rotation around its axis with a change of direction of rotation motion resulting in highly efficient mixing and oxygenation for aerobic cultivation. Combined with a near-infrared optical system, it is possible to register cell growth kinetics non-invasively in real time.

• Reverse–Spin® mixing principle in 50 ml falcon tubes allows to achieve high kLa (h-1) up to 450, which is essential for efficient aerobic cultivation
• Individually controlled bioreactor accelerates optimization process
• Possibility to cultivate microaerophilic and obligate anaerobic microorganisms (not strict anaerobic conditions)
• Reverse–Spin® mixing principle enables non-invasive biomass measurement in real time
• Near-infrared optical system makes it possible to register cell growth kinetics
• Free of charge software for storage, demonstration, and analysis of data in real time
• Compact design with low profile and small footprint for personal application
• Temperature control for bioprocess applications
• Active cooling for rapid temperature control, e.g. for temperature fluctuation experiments
• Task profiling for process automatization
• Cloud data storage to remotely monitor the process of cultivation while at home or using a mobile phone

Software features:
• Real–Time cell growth logging
• 3D graphical representation of OD or growth rate over time over unit
• Pause option
• Save/Load option
• Report option: PDF and Excel
• Connect up to 10 units simultaneously to 1 computer
• Remote monitoring option (requires internet connection)
• Cycling/Profiling options
• User manual calibration possibility for most cells

Typical applications:
• Fermentation real-time growth kinetics
• Clone candidate screening
• Protein expression
• Temperature stress and fluctuation experiments
• Media screening and optimization
• Growth characterization
• Inhibition and toxicity tests
• Strain quality control