fastGEN EGFR/HER2 Cancer Kit
Precision molecular diagnostics for NSCLC patients
The fastGEN EGFR/HER2 Cancer Kit is a new NGS kit designed to detect key mutations in the EGFR and HER2 (ERBB2) genes that play a crucial role in non-small cell lung cancer (NSCLC).
Detection of resistant and rare mutations
The kit enables the detection of activating mutations in the EGFR gene, particularly exon 19 deletions and the L858R point mutation in exon 21, which are associated with sensitivity to EGFR tyrosine kinase inhibitors (TKIs).
In addition to these common variants, it also identifies less frequent mutations such as G719X, L861Q, and insertions in exon 20 (Ex20ins). While G719X and L861Q may show variable response, Ex20ins mutations are typically resistant to conventional TKIs.
The analysis covers both sensitizing and resistant mutations, supporting the selection of the most appropriate targeted therapy.
For the HER2 gene, the kit detects point mutations and insertions in exon 20, which are involved in tumor progression and represent potential targets for therapies such as trastuzumab deruxtecan.
Four reasons why fastGEN is worth your attention
The fastGEN technology provides a method of sensitive, specific and time-efficient examination of the mutational status of clinical markers using NGS technology
Fast
< 30 minutes hand-on time
Reliable
≤ 0.05 significantly lower probability of mistakes
Simple
Ready-to-use Master Mixes
Robust
99-100% high sensitivity and specificity
NGS software solution included
- User-friendliness
- Automatized bioinformatic analysis
- Advanced quality control of sequencing data
- Easy variants filtration
- Local clinical variants database
- Visualization of NGS data
- Internal interpretation of variants and sharing between clinics
- Clinical report generation
- Custom baseline creation
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